By Osamu Hayaishi,Kunihiro Ueda
Comprised of 39 chapters, this publication starts with a ancient heritage at the discovery of poly(ADP-ribose) and the importance of poly- and mono(ADP-ribosyl)ation reactions in molecular biology. the subsequent part explores the position of ADP-ribosylation in NAD metabolism, paying specific cognizance to poly(ADP-ribose) synthetase-DNA interplay and the hyperlink among chromatin constitution and poly(ADP-ribosyl)ation. next chapters specialize in subfractions and subcellular distribution of mono(ADP-ribosyl) proteins in eukaryotic cells; polyadenylylation and ADP-ribosylation of reovirus proteins; poly(ADP-ribose) synthesis in vegetation; and immunohistochemistry of poly(ADP-ribose). the ultimate bankruptcy analyzes the ADP-ribosylation task of toxin A and exoenzyme S in Pseudomonas aeruginosa.
This monograph is written for college students, practitioners, and researchers in fields resembling molecular biology, clinical chemistry, and biochemistry.
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